Endocrine Abstracts

Objective: To assess glucose metabolism (GM) parameters before and after vitamin D treatment in pre-diabetic women.Material and Methods: In the study were included fifty eight women with prediabetes (impaired fasting glucose (IFG) or impaired glucose tolerance (IGT)) aged from 40 to 55 with signed informed consent. The study didn’t include women with diseases affecting the vitamin D metabolism, as well as women receiving regular vitamin D supplemen...

Objective(s): Last data showed advantages of TBS assessment of bone quality over BMD in patients with type 2 diabetes (T2D). We perform DXA in patients with T2D and calculated 10-year probability of fracture using FRAX® tool.Material and methods: A total of 252 (172 females) T2D patients aged 36 to 86 y.o (mean 61.0±8.8) were examined. BMD was performed in 124 patients (110 females) using DXA (Lunar Prodigy, USA). BMD adjusted for TB...

Objective: Recent studies suggest that vitamin D deficiency could be a risk factor for metabolic abnormalities.The aim of this study was to assess the relationship between 25(OH)D level and metabolic syndrome components.Materials and methods: A total of 697 women from 30 to 55 y.o. were examined. Exclusion criteria were, clinically significant endocrine, renal, liver and GI diseases, regular insolation and intake of vitamin D and c...

Objective(s): Vitamin D deficiency and vitamin D receptor (VDR) gene polymorphisms can be associated with atherogenic lipid profile. The results of recent studies in different populations are contradictory. The aim of study was to assess serum lipids in women with different vitamin D status carrying various VDR gene variants.Materials and methods: We examined 697 women aged 35 to 55 y.o. (mean 43.4±0.3). Anthropometric parameters (...

Recently, vitamin D deficiency has been considered as a risk factor for the morbidity and the severity of acute respiratory infections. The aim of this study was to evaluate the interlinks between serum 25(OH)D level and severity of new coronavirus infection (COVID-19) in hospitalized patients.MethodsWe included 131 patients aged 21 to 93 y.o. (mean age 51.7 ± 13.8 years), 76 (57.1%) men, hospitalized following COVID-19 infect...

Hypothesis: The clinical presentation of primary hyperparathyroidism (PHPT) changed lately but we don’t know if more patients in our population have asymptomatic form of PHPT.Materials and methods: Medical records of 449 patients with PHPT who were operated in three Medical Centers (Saint-Petersburg, Russia) between Jan 2011– Jun 2018 were screened. We analyzed anthropometric data, laboratory tests (PTH, 25(OH)D, Ca, iCa, P, 24-h calciuria, ALP...